研究队伍
教 授 柴继杰
教 授 黄善金
教 授 刘 栋
教 授 刘进元
教 授 刘玉乐
研究员 鲁 志
教 授 潘俊敏
教 授 戚益军
研究员 孙前文
教 授 谢道昕
教 授 张大鹏
教 授 颜 宁
研究员 赵 乔

植物抗逆结构生物学实验室主任

颜 宁 博士 教授 国家杰出青年基金获得者
HHMI国际青年科学家

个人简历:

1996-2000
2000-2004
2005-2007
2007-至今
清华大学生物科学与技术系 学士
美国普林斯顿大学分子生物学系 博士
美国普林斯顿大学分子生物学系 博士后
清华大学医学院教授 教授 博士生导师

实验室代表论文:

1.  Dong Deng, Ping Yin, Chuangye Yan, Xiaojing Pan, Xinqi Gong, Shiqian Qi, Tian Xie, Magdy Mahfouz, Jian-Kang Zhu, Nieng Yan#, and Yigong Shi# (2012). Recognition of methlyated DNA by TAL effectors. Cell Research, doi: 10.1038/cr.2012.127. [Epub ahead of print] (# indicates corresponding authors).
2.  Dong Deng, Chuangye Yan, Xiaojing Pan, Magdy Mahfouz, Jiawei Wang, Jian-Kang Zhu, Yigong Shi#, and Nieng Yan# (2012) Structural basis for the specific recognition of DNA by TAL effectors. Science, 335: 720-3 [Epub 2012 Jan 5] (#indicates corresponding authors).
3.  Tian Xie, Ruobing Ren, Yuan-Yuan Zhang, Yuxuan Pang, Chuangye Yan, Xinqi Gong, Yuan He, Wenqi Li, Di Miao, Qi Hao, Haiteng Deng, Zhixin Wang, Jia-Wei Wu, and Nieng Yan. (2012) Molecular mechanism for the inhibition of a critical component in the Arabidopsis thaliana abscisic acid signal transduction pathways, SnRK2.6, by the protein phosphatase ABI1. J. Biol. Chem. 287: 794-802 [Epub 2011 Nov 16]
4.  Wenrong He, Javier Brumos, Hongjiang Li, Yusi Ji, Meng Ke, Xinqi Gong, Qinglong Zeng, Wenyang Li, Xinyan Zhang, Fengying An, Xing Wen, Pengpeng Li, Jinfang Chu, Xiaohong Sun, Cunyu Yan, Nieng Yan, De-Yu Xie, Natasha Raikhel, Zhenbiao Yang, Anna N. Stepanova, Jose M. Alonso, and Hongwei Guo. (2011) A Small-Molecule Screen Identifies L-Kynurenine as a Competitive Inhibitor of TAA1/TAR Activity in Ethylene-Directed Auxin Biosynthesis and Root Growth in Arabidopsis. Plant Cell, 23: 3944-60
5.  Qi Hao, Ping Yin, Wenqi Li, Li Wang Chuangye Yan, Zhaohu Lin, Jim Zhen Wu, Jiawei Wang, S. Frank Yan, and Nieng Yan. (2011) The molecular Basis of ABA-independent inhibition of PP2Cs by a subclass of PYL proteins. Molecular Cell, 42: 662-672.
6.  Xiaoqiu Yuan, Ping Yin, Qi Hao, Chuangye Yan, Wenqi Li, Jiawei Wang, and Nieng Yan. (2010) Single amino acid alteration between isoleucine and valine determinates the pyrabactin selectivity between PYL1 and PYL2. J. Biol. Chem. 285: 28953-8. [July 15th, Epub ahead of print]
7.  Qi Hao, Ping Yin, Xiaoqiu Yuan, Chuangye Yan, Wenqi Li, Jiawei Wang, and Nieng Yan. (2010) Functional mechanism of the ABA agonist pyrabactin. J. Biol. Chem. 285: 28946-52. [June 16th, Epub ahead of print]
8.  Ping Yin, He Fan, Qi Hao, Xiaoqiu Yuan, Di Wu, Yuxuan Pang, Chuangye Yan, Wenqi Li, Jiawei Wang, and Nieng Yan. (2009) Structural insights into the mechanism of abscisic acid signaling by PYL. Nature Structural & Molecular Biology, 16:1230-1236 (Cover and “article of the month”)

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